| 蛋白信息(About this protein) | |
| 名称(Name) | 2019-nCoV Nucleocapsid Protein (新型冠状病毒N蛋白)；1-419aa |
| 别名(Synonyms) | N protein; Nucleocapsid phosphoprotein; Nucleocapsid protein; N structural protein；核衣壳蛋白 |
| 产品简介(Background) | SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. |
| 产品用途(Applications) | 用于新型冠状病毒抑制剂的筛选、抗体制备、ELISA的标准蛋白或结构研究 |
| 外观(Physical appearance) | 液体 |
| 活性(Biological activity) | - |
| 活力单位(Unit definition) | - |
| 浓度(Concentration) | >50μg/ml as determined by Bradford protein assay method. |
| 纯度(Purity) | >90% as determined by SDS-PAGE and Coomassie blue staining. |
| 配方(Formulation) | 25mM Tris, pH8.0, 250mM NaCl, 10% glycerol. |
| 使用方法(Recommended usage) | - |
| 氨基酸序列(Amino acid sequence) | MSDNGPQNQR NAPRITFGGP SDSTGSNQNG ERSGARSKQR RPQGLPNNTA SWFTALTQHG KEDLKFPRGQ GVPINTNSSP DDQIGYYRRA TRRIRGGDGK MKDLSPRWYF YYLGTGPEAG LPYGANKDGI IWVATEGALN TPKDHIGTRN PANNAAIVLQ LPQGTTLPKG FYAEGSRGGS QASSRSSSRS RNSSRNSTPG SSRGTSPARM AGNGGDAALA LLLLDRLNQL ESKMSGKGQQ QQGQTVTKKS AAEASKKPRQ KRTATKAYNV TQAFGRRGPE QTQGNFGDQE LIRQGTDYKH WPQIAQFAPS ASAFFGMSRI GMEVTPSGTW LTYTGAIKLD DKDPNFKDQV ILLNKHIDAY KTFPPTEPKK DKKKKADETQ ALPQRQKKQQ TVTLLPAADL DDFSKQLQQS MSSADSTQA 备注：本氨基酸序列仅供参考，不含N-His序列，实际氨基酸长度或序列可能有一定变化。 |
-20℃保存，一年有效。-80℃保存，两年有效。
注意事项：分装后-20℃或更低温度冻存，以避免反复冻融。
收到产品后请立即按照说明书推荐的条件保存。在打开管盖前，请适当离心，使附着在管盖或管壁上的蛋白聚集于管底。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
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